MRI scanners can be classified on the strength of their magnets. A typical diagnostic scanner is 1.5 Tesla with newer models being 3 Tesla. This study examined the feasibility and value of a 7 Tesla scanner in MS.
- MR imaging at 7 T was safe.
- Cortical and total lesion counts were 97/592 on the 7 Tesla scanner compared with 84/384 on the 3 Tesla scanner; a 15% and 54% increase in lesion number. respectively.
- 205 juxta-cortical lesions were seen with 7 Tesla 3D imagingaing compared to 125 with 2D 3 Tesla imaging; a 64% increase.
- Higher numbers of lesions were also found in the deep white matter using the 7 Tesla scanner: 196 vs. 155; a 26% increase.
“This confirms pathological studies that show that for every lesions seen with the naked eye there are many more lesions seen under the microscope; what is important about this study is that 7 Tesla scanners will allow us to focus on cortical pathology, the substrate that drives cognitive impairment in MS. Let’s hope the newer technology will allow us to visualise B cell follicles on the surface of the brain. If we can do this then we can test the effectiveness of therapies that target such lesions.”