ECTRIMS 2013: safety update #MSBlog #MSResearch
“As promised the following is my safety update that I gave on the SSIF ‘MS Academia: Multiple sclerosis advanced course’ on Tuesday 1st October 2013. The slides should be self-explanatory.”
“As promised the following is my safety update that I gave on the SSIF ‘MS Academia: Multiple sclerosis advanced course’ on Tuesday 1st October 2013. The slides should be self-explanatory.”
What is sudden death? How common is it? Is it primarily occurring in RRMS or progressive MS?
I have posted on this issue in the past:http://multiple-sclerosis-research.blogspot.dk/2012/02/sudden-death-in-ms-or-sudmus-1.htmlhttp://multiple-sclerosis-research.blogspot.dk/2011/12/fingolimod-death.html
Thanks for replying, Prof G. I do, however, feel that your previous posts on sudden death do not put me at ease. After all, you did once say that sudden death in MS "may be much commoner than expected". I do not like the sound of that. Then again, I guess a disease as severe as MS probably doesn't have the best outcome.
Thank you for sharing the slides with us. Most of them were not as self explanatory to me as they would be to a doctor, but I did understand slide 9, I think! It seems to suggest that a diagnostic test, and perhaps even a treatment suggested by the test, is useful if the results are 80% accurate.Simpson's Paradox,(see link to Wickipedia) shows that this approach can be inadequate if further tests are not carried out to confirm the diagnosis. Further analysis of the figures is needed to arrive at the correct solution. The link gives several simple examples, including treatment of kidney stones, where the analysis initially gives the wrong result until the figures making them up are probed more deeply. You guys in research are probably fully aware of this, but it is worth considering!http://en.wikipedia.org/wiki/Simpson's_paradox