Background: This study is based on the published literature relating to the effects of vitamin D in reducing the risk of cancer, cardiovascular disease and respiratory infections (please note MS was not included in the overall analysis). These vitamin D-sensitive diseases account for more than half of global deaths due to cancer, respiratory infections and diseases, tuberculosis and diabetes.
Additional vitamin D-sensitive diseases such as Alzheimer’s disease, falls, meningitis, Parkinson’s disease, maternal sepsis, maternal hypertension (pre-eclampsia) and multiple sclerosis only account for 2-3% of global death.
Results: Increasing blood vitamin D levels from 54 to 110 nmol/l would reduce the vitamin D-sensitive disease death rate by an estimated 20%.
Conclusions: Increasing blood vitamin D levels is the most cost-effective way to reduce global death rates, as the cost of vitamin D is very low and there are few side effects from oral intake and/or frequent moderate sun exposure with sufficient body surface area exposed.
“Wow, this is an important piece of work or modeling. Now you see why I don’t stop banging the vitamin D drum; it is not only important for MS but a large number of other diseases.”
“How do we get our vitamin D levels to 110nmol/L? Live in a country with a lot of sun and take-up an outdoor job and stop using sun block. Or you could simply take vitamin D supplements at a dose of 5,000U per day.”
“George Eber’s in Oxford estimates that we may be able to reduce the worldwide incidence of MS by up to 85% if we could make the world population vitamin D replete. Other feels this figure is on the high side and quote estimates of 40% to 60%. What do you think? I think we need a national vitamin D prevention study to convince public health officials to take up the baton.”
Epub ahead of print: Grant WB. An estimate of the global reduction in mortality rates through doubling vitamin D levels. Eur J Clin Nutr. 2011 Jul 6. doi: 10.1038/ejcn.2011.68.
Extra reading: Vitamin D
Please see other postings on this blog about vitamin D:
05 Jul 2011
Vitamin D – some facts. Vitamin D is a misnomer; it was incorrectly classified as a vitamin. Vitamins: are nutrients that are required in tiny amounts; cannot be synthesised in sufficient quantities by our bodies …
05 Jul 2011
Vitamin D and multiple sclerosis hospital admissions in Scotland. In this study there is a link between hospital admissions due to MS in Scotland and the average vitamin D levels in the previous 4 months. …
05 Jul 2011
Vitamin D websites. You may find these websites helpful: Vitamin D Council & Vitamin D3 World CoI: Nil. Posted by Gavin Giovannoni at 09:38 · Email This BlogThis! Share to Twitter Share to Facebook Share to Google Buzz …
20 Jun 2011
Previous studies have shown that serum vitamin D levels are genetically influenced. Therefore variations or polymorphisms in vitamin D pathway genes are candidates for association with MS susceptibility. …
01 Jun 2011
Efficacy of vitamin D(3) as add-on therapy in patients with relapsing-remitting multiple sclerosis receiving subcutaneous interferon beta-1a: A Phase II, multicenter, double-blind, randomized, placebo-controlled trial. …
07 Jul 2011
Sunlight, Vitamin D and EBV. More about the environmental risk factors that increase susceptibility to MS. “What we now need is a study to integrate these risk factors. Would you be interested in participating?” …
03 May 2011
Vitamin D Supplement Doses and Serum 25-Hydroxyvitamin D in the Range Associated with Cancer Prevention. How safe are high dose Vitamin D3 (vD3) supplements? In this study on over 3600 study participants ~25% of the …
28 Jun 2011
The active metabolite of vitamin D is a potent modulator of immune cells. In this study the investigators’ determined whether vitamin D, a sun-dependent nutrient can affect the cells athat are associated with the immune …
Etc. There are lot more posts on this subject (please use the search engine above to get to them)